Table 1 Design and sample characteristics of the two questionnaires
From: Prognosis research ideally should measure time-varying predictors at their intended moment of use
| Â | PROG-RES | POST |
|---|---|---|
Design | Prospective observational cohort | Cluster RCT |
Registration | (Protocol [21]) | Current Controlled Trials ISRCTN40721988 |
Intervention | Usual care | I: ultra-brief screening questions for anxiety and depression + pain intensity measurement C: screen for pain intensity |
Setting | 5 general practices in North Staffordshire, England | 45 general practices in West Midlands, England |
Period of recruitment | Sep 2006–Apr 2007 | Sep 2011–Nov 2012 |
Inclusion criteria | Consecutive patients aged 50+ years consulting for non-inflammatory musculoskeletal pain | Consecutive patients aged 45+ years consulting for suspected or diagnosed peripheral joint osteoarthritis |
Exclusion criteria | Vulnerable patient (e.g. diagnosed with dementia); recent trauma associated with significant injury; inflammatory arthropathy | Vulnerable patient (e.g. diagnosed with a terminal illness); nursing home resident; recent trauma associated with significant injury; inflammatory arthropathy, crystal disease, SpA, PMR |
Data collection pointsa | In GP consultation (point of care), post-consultation questionnaire, 3Â months, 6Â months, 12Â months, 24Â months, 36Â months | In GP consultation (point of care), post-consultation questionnaire, 3Â months, 6Â months, 12Â months |
Candidate predictor of interest | Current pain intensity (0–10 NRS [23]) | |
Timing of predictor measurement | 1. Point of care 2. Post-consultation questionnaire | |
Outcome of interest | Patient global rating of change at 6Â months (completely recovered/much improved/improved vs same/worse/much worse [22]) | |
Participants eligible for inclusion in main analyses | 296 | 756 |
Age (years): mean (SD) | 64.8 (9.8) | 65.8 (9.9) |
Male: no. (%) | 120 (40.5) | 339 (44.8) |
Current pain intensity at point of care (0–10): mean (SD) | 5.9 (2.2) | 6.2 (2.1) |
Current pain intensity in questionnaire (0–10): mean (SD) | 5.5 (2.6) | 5.3 (2.6) |
Interval between point of care and return of questionnaire (days): median (IQR; range) | 17 (13, 27; 6–75) | 21 (16, 30; 3–81) |
Unfavourable outcome at 6Â months: no. (%) | 144 (48.7) | 412 (54.5) |