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Table 4 Coefficients (and 95% confidence intervals) of the variables used to calculate the Kidney Donor Risk Index from the original development, the updated Cox proportional hazards model and the updated cause-specific Cox model

From: An external validation of the Kidney Donor Risk Index in the UK transplant population in the presence of semi-competing events

Variable

Original

Updated (Cox model)

Updated (cause-specific Cox model)

Age-18; for donors under 18 years

− 0.019 (− 0.031, − 0.010)

− 0.032 (− 0.096, 0.033)

− 0.031 (− 0.095, 0.033)

Age-40, years

0.013 (0.011, 0.015)

0.016 (0.009, 0.024)

0.016 (0.009, 0.024)

Age-50; for donors over 50 years

0.011 (0.005, 0.016)

0.003 (− 0.010, 0.016)

0.003 (− 0.010, 0.016)

Height per 10 cm increase

− 0.046 (− 0.062, − 0.031)

− 0.034 (− 0.093, 0.026)

− 0.034 (− 0.093, 0.026)

Weight per 5 kg increase; for donors below 80 kg

− 0.020 (− 0.031, − 0.010)

− 0.035 (− 0.068, − 0.002)

− 0.035 (− 0.068, − 0.002)

Ethnicity

 Not Black ethnic origin

Reference

 Black ethnic origin

0.179 (0.122, 0.239)

0.409 (− 0.017, 0.835)

0.405 (− 0.021, 0.832)

History of hypertension

 No

Reference

 Yes

0.126 (0.077, 0.174)

0.256 (0.135, 0.378)

0.255 (0.133, 0.376)

History of diabetes

 No

Reference

 Yes

0.130 (0.039, 0.215)

0.154 (− 0.050, 0.358)

0.153 (− 0.051, 0.357)

Cause of death CVA

 No

Reference

 Yes

0.088 (0.039, 0.131)

 − 0.035 (− 0.308, 0.238)

 − 0.036 (− 0.309, 0.237)

Creatinine-1, mg/dl

0.220 (0.157, 0.285)

0.395 (0.205, 0.586)

0.395 (0.204, 0.586)

Creatinine-1; for donors with creatinine > 1.5, mg/dl

 − 0.209 (− 0.301, − 0.117)

 − 0.500 (− 0.819, − 0.182)

 − 0.500 (− 0.818, − 0.181)

HCV

 Negative

Reference

 Positive

0.240 (0.122, 0.358)

0.233 (− 1.286, 1.751)

0.234 (− 1.284, 1.753)

Donor type

 DBD

Reference

 DCD

0.133 (0.020, 0.247)

0.113 (0.005, 0.221)

0.112 (0.004, 0.220)

  1. Variables are centred as they were in the original publication
  2. CVA cerebrovascular accident, DBD deceased brain donor, DCD deceased cardiac donor