Table 2 Six consequences of using BBS instead of VBS for a single new diagnostic test
| Â | Â | Test has a value | Test has no value |
|---|---|---|---|
1) | Test-positive patients can benefit from i + | Starts earlier by Δ+Δ b | Starts earlier by Δ+Δ b |
2) | Harm to test-positive patients by exposure to i + | Starts earlier by Δ+Δ b | Starts earlier by Δ+Δ b |
3) | Test-negative patients can benefit from i + | Not applicable | Delayed by Δ v |
4) | Harm to all patients by exposure to test | Starts earlier by Δ+Δ b | In a period of length Δ+Δ b +Δ v |
5) | Use of resources for testing all patients | Starts earlier by Δ+Δ b | In a period of length Δ+Δ b +Δ v |
6) | Additional off-label use | In a period of length Δ+Δ b +Δ v —harm to patients probable | In a period of length Δ+Δ b —harm to patients less probable |