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Table 4 Prevalence of individual ICPC codes (index predictors) and manually verified diagnoses (reference predictors) and measures of misclassification

From: The effects of misclassification in routine healthcare databases on the accuracy of prognostic prediction models: a case study of the CHA2DS2-VASc score in atrial fibrillation

 

ICPC codes (index predictors)

Manually verified diagnoses (reference predictors)

Kappa

Sensitivity

Specificity

PPV

NPV

Congestive heart failure/LV dysfunction

28.1

18.3

56.1

54.5

95.7

83.3

84.3

Hypertension

60.8

59.9

70.9

87.8

83.3

89.1

81.6

Diabetes

24.3

22.5

89.7

88.6

98.8

95.8

96.4

Stroke/TIA/TE

18.7

16.4

75.5

74.8

97.1

85.5

94.4

Vascular disease

34.6

26

60.4

63.1

93.7

84.2

82.7

  1. ICPC International Classification of Primary Care, PPV positive predictive value, NPV negative predictive value