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Table 5 The ten best biomarker pairs in the TRIBE-AKI study

From: Using ordinal outcomes to construct and select biomarker combinations for single-level prediction

Biomarkers

AUC (Severe)

AUC (Mild)

Urine IL-18

Plasma NT-proBNP

0.8575

0.6125

Plasma h-FABP

Urine IL-18

0.8495

0.6394

Plasma h-FABP

Plasma BNP

0.8464

0.6403

Plasma h-FABP

Plasma NT-proBNP

0.8459

0.6329

Urine IL-18

Plasma BNP

0.8414

0.6168

Plasma h-FABP

Urine KIM-1

0.8410

0.6400

Plasma h-FABP

Plasma IL-6

0.8365

0.6757

Plasma h-FABP

Plasma IL-10

0.8342

0.6405

Plasma h-FABP

Plasma CKMB

0.8271

0.6558

Urine KIM-1

Plasma TNTHS

0.8253

0.6005

  1. The table presents the ten pairs with the highest estimated AUC for severe vs. no/mild AKI. The estimated AUCs for severe vs. no/mild AKI and for mild vs. no AKI are presented. Both estimates are corrected for optimism due to resubstitution bias
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Diagnostic and Prognostic Research

ISSN: 2397-7523

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