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Table 3 Univariate sensitivity analysis showing the savings (when compared to RT-PCR testing) for the minimum and maximum values of each parameter. Top panel: Strategy 2, NPT testing with nasal swabs. Bottom panel: Strategy 3, NPT testing with throat swabs

From: Cost implications for the NHS of using the Alere™ i Influenza A & B near patient test with nasal swabs

 

Savings (min value of parameter)

Savings (max value of parameter)

Savings range

Strategy 2. NPT testing with nasal swabs

   

 Length of stay no flu (1–5)

£64,822

£327,540

£262,718

 Isolation cost (£44.22–£132.65)

£100,747

£291,615

£190,867

 Probability of isolation with flu (0–1)

£5936

£196,181

£190,245

 Prevalence (0–0.4)

£165,067

£238,276

£73,210

 Specificity nasal swabs (0.7–0.96)

£172,883

£219,479

£46,596

 Sensitivity nasal swabs (0.8–1)

£200,848

£195,248

£5601

 Probability of nosocomial infection (0–0.4)

£196,803

£195,559

£1245

 Length of stay with flu (3–7)

£195,580

£196,782

£1203

Strategy 3. NPT testing with throat swabs

   

 Length of stay no flu (1–5)

£69,939

£378,916

£308,977

 Isolation cost (44.215–132.645)

£112,399

£336,457

£224,059

 Probability of isolation with flu (0–1)

£623

£224,428

£223,805

 Prevalence (0–0.4)

£193,314

£266,523

£73,210

 Specificity throat swabs (0.7–1)

£201,596

£231,883

£30,288

 Probability of nosocomial infection (0–0.4)

£231,957

£216,898

£15,059

 Sensitivity throat swabs (0.8–0.86)

£226,055

£222,734

£3321

 Length of stay with flu (3–7)

£224,428

£224,428

£0