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Table 3 Univariate sensitivity analysis showing the savings (when compared to RT-PCR testing) for the minimum and maximum values of each parameter. Top panel: Strategy 2, NPT testing with nasal swabs. Bottom panel: Strategy 3, NPT testing with throat swabs

From: Cost implications for the NHS of using the Alere™ i Influenza A & B near patient test with nasal swabs

  Savings (min value of parameter) Savings (max value of parameter) Savings range
Strategy 2. NPT testing with nasal swabs    
 Length of stay no flu (1–5) £64,822 £327,540 £262,718
 Isolation cost (£44.22–£132.65) £100,747 £291,615 £190,867
 Probability of isolation with flu (0–1) £5936 £196,181 £190,245
 Prevalence (0–0.4) £165,067 £238,276 £73,210
 Specificity nasal swabs (0.7–0.96) £172,883 £219,479 £46,596
 Sensitivity nasal swabs (0.8–1) £200,848 £195,248 £5601
 Probability of nosocomial infection (0–0.4) £196,803 £195,559 £1245
 Length of stay with flu (3–7) £195,580 £196,782 £1203
Strategy 3. NPT testing with throat swabs    
 Length of stay no flu (1–5) £69,939 £378,916 £308,977
 Isolation cost (44.215–132.645) £112,399 £336,457 £224,059
 Probability of isolation with flu (0–1) £623 £224,428 £223,805
 Prevalence (0–0.4) £193,314 £266,523 £73,210
 Specificity throat swabs (0.7–1) £201,596 £231,883 £30,288
 Probability of nosocomial infection (0–0.4) £231,957 £216,898 £15,059
 Sensitivity throat swabs (0.8–0.86) £226,055 £222,734 £3321
 Length of stay with flu (3–7) £224,428 £224,428 £0