From: Methods for Evaluation of medical prediction Models, Tests And Biomarkers (MEMTAB) 2018 Symposium
 | Model including all variables | Model after variable selection | ||
---|---|---|---|---|
Beta | OR (95% CI) | Betaa | OR (95% CI) | |
Intercept | ||||
 Study 1 | -7.9 |  | -4.6 |  |
 Study 2 | -8.5 |  | -5.3 |  |
 Study 3 | -9.0 |  | -5.7 |  |
 Study 4 | -8.7 |  | -5.4 |  |
 Study 5 | -9.3 |  | -6.0 |  |
Quantitative fetal fibronectin (qfFN)b | ||||
 (qfFN+1)/100)^0.5 | 2.0 | 7.6 (5.7 – 10) | 1.89 | 6.6 (4.9 – 8.9) |
Age (yr) | 0.02 | 1.0 (0.98 – 1.1) | - | - |
BMI (kg/m2) | 0.02 | 1.0 (0.96 – 1.1) | - | - |
Smoking | -0.66 | 0.52 (0.24 – 1.1) | -0.67 | 0.51 (0.24 – 1.08) |
Ethnicity | ||||
 1 Caucasian | Reference |  | Reference |  |
 2 South Asian | 1.1 | 2.9 (0.93 – 9.1) | 0.94 | 2.6 (0.84 – 7.9) |
 3 East Asian | -1.2 | 0.31 (0.04 – 2.5) | -1.004 | 0.37 (0.05 – 2.8) |
 4 African, Caribbean, Middle-East | -0.21 | 0.81 (0.42 – 1.5) | -0.21 | 0.81 (0.43 – 1.5) |
 5 Other | -0.25 | 0.78 (0.20 – 3.0) | -0.31 | 0.74 (0.19 – 2.8) |
Nulliparity | 0.53 | 1.7 (1.1 – 2.7) | 0.37 | 1.4 (0.92 – 2.2) |
Multiple pregnancy | 0.85 | 2.3 (1.4 – 4.1) | 0.83 | 2.3 (1.3 – 3.9) |
Previous spontaneous PTD < 34 weeks | 0.43 | 1.5 (0.78 – 1.1) | - | - |
Gestational age at assessment (wks) | 0.03 | 1.0 (0.96 – 1.1) | - | - |
Nagelkerke R2 | 0.39 | 0.39 | ||
AUC (95%CI) | 0.90 (95% CI 0.88 – 0.93) | 0.89 (95% CI 0.87 – 0.93) |