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Table 2 (abstract P25). Facilitators of spin in clinical studies evaluating performance of biomarkers in ovarian cancer

From: Methods for Evaluation of medical prediction Models, Tests And Biomarkers (MEMTAB) 2018 Symposium

Potential facilitators of spin

Spin frequency, n= 200

n (%) [95% CI]

Not stating sample size calculations

200 (100% [98% - 100%])

Not mentioning potential harms

200 (100% [98% - 100%])

Not pre-specifying a positivity threshold for continuous biomarker

84/164* (51.2% [43% - 59%])

Incomplete or not reporting imprecision or statistical test for data shown

26 (13% [9% - 19%])

Study objective not reported or unclear

24 (12% [8% - 18%])

  1. * 164 articles included evaluation of continuous biomarkers