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Table 1 (abstract P56). See text for description

From: Methods for Evaluation of medical prediction Models, Tests And Biomarkers (MEMTAB) 2018 Symposium

Study N Comparator tool Index test Additional TP FP TN FN NNS
Zeller 2014 12,650
CVD: 853
No CVD: 11,797
ASSIGN SCORE variables ASSIGN +
hs-cTn
TP 83 FN 42
TN 564 FP 537
Increase in TP rate 41/853 = 4.8% (3.37–6.23)
Increase in TN rate 27/11797 = 0.2% (0.12–0.28)
TP:FP = 1:6.5
TN:FN = 13.4:1
ASSIGN 218
ASSIGN +
hs-cTn
198
Blanken-berg
2016
60,444
CVD: 3178
No CVD: 57,266
ESC SCORE variables ESC SCORE +
hs-cTn
TP 64 FN 31
TN 461 FP 362
Increase in TP rate 33/3178 = 1.0% (0.65–1.35)
Increase in TN rate 99/57266 = 0.2% (0.16–0.24)
TP:FP = 1:5.7
TN:FN = 14.9:1
ESC SCORE
237
ESC SCORE +
hs-cTn
233