Table 1 (abstract P56). See text for description
From: Methods for Evaluation of medical prediction Models, Tests And Biomarkers (MEMTAB) 2018 Symposium
Study | N | Comparator tool | Index test | Additional TP FP TN FN | NNS |
|---|---|---|---|---|---|
Zeller 2014 | 12,650 CVD: 853 No CVD: 11,797 | ASSIGN SCORE variables | ASSIGN + hs-cTn | TP 83 FN 42 TN 564 FP 537 Increase in TP rate 41/853 = 4.8% (3.37–6.23) Increase in TN rate 27/11797 = 0.2% (0.12–0.28) TP:FP = 1:6.5 TN:FN = 13.4:1 | ASSIGN 218 ASSIGN + hs-cTn 198 |
Blanken-berg 2016 | 60,444 CVD: 3178 No CVD: 57,266 | ESC SCORE variables | ESC SCORE + hs-cTn | TP 64 FN 31 TN 461 FP 362 Increase in TP rate 33/3178 = 1.0% (0.65–1.35) Increase in TN rate 99/57266 = 0.2% (0.16–0.24) TP:FP = 1:5.7 TN:FN = 14.9:1 | ESC SCORE 237 ESC SCORE + hs-cTn 233 |