OPTimal IMAging strategy in patients suspected of non-traumatic pulmonary disease at the emergency department: chest X-ray or ultra-low-dose CT (OPTIMACT)—a randomised controlled trial chest X-ray or ultra-low-dose CT at the ED: design and rationale

Table 1 SPIRIT OPTIMACT study scheme

Time scheme OPTIMACT study
	Enrolment	Allocation
Time point	t ₀	t ₀	T ₂₈
Enrollment	Day 0 ED	Day 0 ED	Day 28
Eligibility screen	X
Informed consent	X
Allocation		Block randomization per month
Interventions
Intervention A: chest X-ray		A or B
Intervention B: ULD chest CT
Assessments
Standardized clinical history		X
Standardized physical examination		X
Predefined laboratory set: WBC, glucose, urea, and CRP		X
Suspected of CAP Laboratory set etiology pneumonia		X^*
Standardized radiology report		X
Clinical diagnosis at discharge from ED		X
Suspected of CAP Treatment decision regarding antibiotic use*		X^*
Events possibly related to the study procedure		X
Time to preliminary imaging result		X
Time spent at ED		X
Diagnosis at discharge based on data day 28			X
Length of hospital stay			X
Suspected of CAP Antibiotic use			X^*
Follow-up because of incidental findings on chest X-ray or ULD chest CT			X
Mortality 28 days			X
SF12/EQ-5D-5L			X
Health care costs			X
iMCQ			X
iPCQ			X

ISSN: 2397-7523