|
Selection approach
|
No of SNPs selected
|
Training set (419)
|
Testing set (n = 204)
|
|---|
|
Original c-index
|
Corrected c-index*
|
c-index* (95% CI)
|
|---|
|
ISIS-LASSO
|
2
|
0.649
|
0.646
|
0.664 (0.621–0.707)
|
|
ISIS-ALASSO
|
0
|
0.649
|
0.650
|
0.671 (0.624–0.719)
|
|
ISIS-RSF
|
2
|
0.650
|
0.645
|
0.669 (0.618–0.720)
|
|
SIS
|
2
|
0.650
|
0.646
|
0.669 (0.624–0.714)
|
|
SIS-LASSO
|
0
|
0.649
|
0.649
|
0.671 (0.626–0.717)
|
|
SIS-ALASSO
|
0
|
0.649
|
0.650
|
0.671 (0.620–0.723)
|
|
SIS-RSF
|
2
|
0.650
|
0.648
|
0.669 (0.623–0.716)
|
|
PSIS
|
40
|
0.749
|
–
|
0.572 (0.527–0.617)
|
|
PSIS-LASSO
|
28
|
0.746
|
0.727
|
0.568 (0.524–0.613)
|
|
PSIS-ALASSO
|
24
|
0.744
|
0.727
|
0.573 (0.528–0.617)
|
|
PSIS-RSF
|
35
|
0.748
|
–
|
0.575 (0.529–0.622)
|
|
LASSO
|
16
|
0.716
|
–
|
0.586 (0.540–0.632)
|
|
ALASSO
|
13
|
0.653
|
0.634
|
0.647 (0.601–0.693)
|
- *Based on 200 bootstrapped samples
