A PCR-based diagnostic testing strategy to identify carbapenemase-producing Enterobacteriaceae carriers upon admission to UK hospitals: early economic modelling to assess costs and consequences

Table 1 Resource use items and costs

Cost item	Unit cost (£)	Source
Culture testing (staff & test costs)	8.79	Expert clinical input^a
PCR testing (including DNA extraction) (staff & test costs)	39.59	Expert clinical input^a
Consumables for swabbing	3.62	MRSA Pathfinder (Scotland) 2008/2009 [13]
Presumptive confirmation by phenotypic test (Carba NP) (staff & test costs)	2.78	Yusuf, E. et al. (2014) [10]
Species identification by MALDI-TOF (staff & test costs)	1.92	Tran, A. et al. (2015) [11]
Referral to AMRHAI reference laboratory (staff & consumable costs)	0.65	Expert clinical input^a
Antibiotic susceptibility testing (staff & consumable costs)	3.99	Expert clinical input^a
Non-elective bed day	303.74	NHS reference costs 2016/2017 [14]
Isolation room bed day^b	100.12	MRSA Pathfinder (Scotland) 2008/2009 [13]
Contact precaution per day	22.12	MRSA Pathfinder (Scotland) 2008/2009 [13]

^aCost based on information provided by a microbiology laboratory manager at the Newcastle upon Tyne Hospitals NHS Foundation Trust. Costs are likely to be representative of other tertiary hospitals, however they may vary
^bIsolation room bed day costs incurred in addition to non-elective bed day costs

ISSN: 2397-7523