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Table 3 Sensitivity analyses expected costs and test performance

From: A PCR-based diagnostic testing strategy to identify carbapenemase-producing Enterobacteriaceae carriers upon admission to UK hospitals: early economic modelling to assess costs and consequences

Strategy

Expected cost per patient (£)

True positives (%)

False positives (%)

True negatives (%)

False negatives (%)

Sensitivity Analysis (a):

 Culture testing

1916.00

0.5

6.7

92.7

0.0996

 PCR testing

1704.24

0.6

3.4

96.0

0.024

 Cost difference with PCR testing (£)

−211.76

    

Sensitivity Analysis (b):

 Culture testing

5639.07

0.6

18.7

80.7

0.0027

 PCR testing

4791.70

0.6

3.4

96.0

0.024

 Cost difference with PCR testing (£)

−847.37

    

Sensitivity Analysis (c):

 Culture testing

2165.82

5.0

17.8

77.2

0.023

 PCR testing

1724.94

4.8

3.2

91.8

0.2

 Cost difference with PCR testing (£)

−440.88

    

Sensitivity Analysis (d):

 Culture testing

2166.37

0.6

18.7

80.7

0.0027

 PCR testing

1696.29

0.6

1.8

97.6

0

 Cost difference with PCR testing (£)

−470.08

    

Sensitivity Analysis (e):

 Culture testing

2166.37

0.6

18.7

80.7

0.0027

 PCR testing

1744.65

0.6

3.4

96

0.024

 Cost difference with PCR testing (£)

−421.72

    

Sensitivity Analysis (f):

 Culture testing

2166.37

0.6

18.7

80.7

0.0027

 PCR testing

1821.65

0.6

3.4

96

0.024

 Cost difference with PCR testing (£)

−344.72

   Â