First-trimester ultrasound measurements and maternal serum biomarkers as prognostic factors in monochorionic twins: a cohort study

Table 4 Predicted risk of developing a fetal adverse outcome according to potential prognostic factor measurements determined a priori

Potential prognostic factor measurement	Predicted risk*
NT (% discordance) 0%	0.446
NT (% discordance) 20%	0.604
CRL (% discordance) 0%	0.379
CRL (% discordance) 10%	0.750
AFP 50th centile (29.3 U/mL)	0.549
AFP 95th centile (54.7 U/mL)	0.658
PlGF 50th centile (60.4 pg/mL)	0.535
PlGF 5th centile (23.6 U/mL)	0.634
sFlt-1 50th centile (2169 pg/mL)	0.545
sFlt-1 95th centile (4089 pg/mL)	0.549

*Risk predictions obtained from the fitted multivariable model for values shown and using the mean values of the standard factors included in the model: 30 years old, BMI 25, non-smoker, Caucasian, nulliparous, and natural conception

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