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Table 1 Baseline characteristics

From: Would treatment decisions about secondary prevention of CVD based on estimated lifetime benefit rather than 10-year risk reduction be cost-effective?

 

All patients

% Patients with the highest expected lifetime benefit

% Patients with the highest expected 10-year risk reduction

n = 10,000

n = 500

n = 1000

n = 2000

n = 500

n = 1000

n = 2000

Age (years)

61 (8)

51 (5)

52 (5)

54 (6)

65 (8)

64 (8)

64 (8)

Male gender

7366 (74%)

274 (55%)

598 (60%)

1259 (63%)

346 (69%)

718 (72%)

1479 (74%)

Current smoking

3137 (31%)

116 (23%)

240 (24%)

531 (27%)

242 (48%)

471 (47%)

907 (45%)

Type 2 diabetes mellitus

1775 (18%)

46 (9%)

105 (11%)

210 (11%)

144 (29%)

280 (28%)

506 (25%)

Systolic blood pressure (mmHg)

140 (20)

142 (21)

141 (21)

140 (21)

150 (22)

148 (22)

146 (22)

Total cholesterol (mmol/L)

4.7 (4.0–5.6)

6.6 (5.9– 7.2)

6.2 (5.6–6.9)

5.9 (5.2–6.6)

6.9 (6.3–7.6)

6.4 (5.8–7.1)

6.0 (5.3–6.7)

Creatinine (umol/L)

89 (70–111)

90 (75–108)

90 (74–111)

90 (72–110)

107 (86–129)

106 (85–128)

103 (84–125)

1 location of CVD

7929 (79%)

414 (83%)

828 (83%)

1636 (82%)

284 (57%)

602 (60%)

1288 (64%)

2 location of CVD

1998 (20%)

86 (17%)

172 (17%)

359 (18%)

211 (42%)

386 (39%)

696 (35%)

3 location of CVD

73 (1%)

0 (0%)

0 (0%)

5 (0%)

5 (1%)

12 (1%)

16 (1%)

Coronary heart disease

6191 (62%)

314 (63%)

627 (63%)

1253 (63%)

339 (68%)

659 (66%)

1295 (65%)

Cerebrovascular disease

3110 (31%)

140 (28%)

299 (30%)

600 (30%)

155 (31%)

314 (31%)

663 (33%)

Peripheral artery disease

1924 (19%)

84 (17%)

163 (16%)

344 (17%)

130 (26%)

258 (26%)

467 (23%)

Abdominal aortic aneurysm

919 (9%)

48 (10%)

83 (8%)

172 (9%)

97 (19%)

179 (18%)

303 (15%)

Atrial fibrillation

278 (3%)

1 (0%)

3 (0%)

6 (0%)

32 (6%)

65 (7%)

106 (5%)

Chronic heart faillure

486 (5%)

7 (1%)

15 (2%)

42 (2%)

61 (12%)

117 (12%)

190 (10%)

  1. All data are displayed as mean ± SD, median (Inter quartile range) or n (%)
  2. *Locations of CVD: The number of locations of vascular disease (i.e. coronary heart disease, cerebrovascular disease, peripheral artery disease, or abdominal aortic aneurysm and combinations)