Table 1 Baseline characteristics of each female cohort
Development (n = 1,865,079) | Validation (n = 100,000) | Contemporary (n = 387,557) | ||
|---|---|---|---|---|
Outcome | Total CVD events | 82 065 | 4482 | NA |
Total follow-up (years) | 13 098 449 | 703 471 | NA | |
Age | 43.07 (15.94) | 43.14 (15.96) | 48.38 (14.43) | |
Systolic blood pressure | 123.91 (18.28) | 124 (18.22) | 123.97 (15.17) | |
Body mass index | 25.6 (5.60) | 25.56 (5.56) | 27.1 (6.31) | |
Cholesterol/high-density lipoprotein ratio | 3.72 (1.20) | 3.72 (1.21) | 3.46 (1.04) | |
Smoking status | Never | 56.04% | 56.15% | 46.05% |
Ex | 16.97% | 16.98% | 31.66% | |
Current | 27.00% | 26.87% | 22.29% | |
Townsend | 1 (least deprived) | 21.96% | 21.96% | 24.95% |
2 | 21.99% | 21.81% | 22.35% | |
3 | 21.17% | 21.46% | 21.56% | |
4 | 20.46% | 20.36% | 18.70% | |
5 (most deprived) | 14.42% | 14.41% | 12.44% | |
Treated hypertension | 6.18% | 6.19% | 8.45% | |
Family history of CVD | 15.08% | 15.13% | 20.86% | |
Type 2 diabetes | 1.16% | 1.19% | 1.15% |