Table 2 Estimated regression coefficients (95% CIs) from the fitted models
| Â | Pre-treatment | Dynamic | ||
|---|---|---|---|---|
Separate | Joint | Separate | Joint | |
Number of oocytes submodel | ||||
 Intercept | 2.09 (2.07 to 2.12) | 2.10 (2.07 to 2.13) | 2.09 (2.07 to 2.12) | 2.09 (2.07 to 2.12) |
 Age (years) | − 0.04 (− 0.05 to − 0.04) | − 0.04 (− 0.05 to − 0.04) | − 0.04 (− 0.05 to − 0.04) | − 0.04 (− 0.05 to − 0.04) |
 Partner age (years) | 0.01 (0.00 to 0.01) | 0.01 (0.00 to 0.01) | 0.01 (0.00 to 0.01) | 0.00 (0.00 to 0.01) |
 Attempt number: 1st | 0 | 0 | 0 | 0 |
 2nd | 0.06 (0.01 to 0.12) | 0.06 (0.01 to 0.11) | 0.06 (0.01 to 0.12) | 0.08 (0.03 to 0.13) |
 3rd | 0.17 (0.07 to 0.27) | 0.14 (0.04 to 0.23) | 0.17 (0.06 to 0.28) | 0.15 (0.06 to 0.24) |
 4th or 5th | 0.02 (− 0.24 to 0.29) | 0.04 (− 0.20 to 0.27) | 0.02 (− 0.24 to 0.26) | 0.16 (− 0.07 to 0.38) |
Fertilisation rate submodel | ||||
 Intercept | − 1.04 (− 1.06 to − 1.01) | − 0.95 (− 0.98 to − 0.92) | − 1.04 (− 1.07 to − 1.01) | − 0.96 (− 0.99 to − 0.93) |
 Age (years) | 0.01 (0.01 to 0.02) | 0.02 (0.01 to 0.03) | 0.01 (0.01 to 0.02) | 0.02 (0.01 to 0.02) |
 Partner age (years) | 0.00 (− 0.01 to 0.00) | − 0.00 (− 0.01 to 0.00) | 0.00 (− 0.01 to 0.00) | 0.00 (− 0.01 to 0.00) |
Embryo evenness submodel | ||||
 Intercepts (log odds of ≤ k): k = 1 | − 4.23 (− 4.37 to − 4.10) | − 4.35 (− 4.50 to − 4.20) | − 4.32 (− 4.47 to − 4.18) | − 4.33 (− 4.48 to − 4.18) |
 K = 2 | − 1.28 (− 1.37 to − 1.19) | − 1.38 (− 1.48 to − 1.29) | − 1.37 (− 1.47 to − 1.27) | − 1.37 (− 1.47 to − 1.26) |
 K = 3 | 1.43 (1.34 to 1.51) | 1.33 (1.24 to 1.42) | 1.34 (1.25 to 1.44) | 1.35 (1.25 to 1.46) |
 Age (years) | 0.01 (− 0.01 to 0.02) | 0.00 (− 0.01 to 0.02) | 0.00 (− 0.01 to 0.02) | 0.00 (− 0.03 to 0.03) |
 Partner age (years) | 0.01 (0.00 to 0.02) | 0.01 (0.00 to 0.02) | 0.01 (0.00 to 0.02) | 0.01 (0.00 to 0.02) |
 Sperm injected into egg | − 0.21 (− 0.32 to − 0.10) | − 0.27 (− 0.38 to − 0.16) | − 0.28 (− 0.39 to − 0.16) | − 0.26 (− 0.37 to − 0.14) |
 Number of oocytes | – | – | 0.09 (0.01 to 0.17) | 0.16 (− 0.17 to 0.53) |
 Fertilisation rate | – | – | − 0.16 (− 0.23 to − 0.08) | − 0.47 (− 0.71 to − 0.21) |
Embryo fragmentation submodel | ||||
 Intercepts (log odds of ≤ k): k = 1 | − 4.91 (− 5.10 to − 4.74) | − 5.11 (− 5.29 to − 4.92) | − 5.06 (− 5.24 to − 4.88) | − 5.06 (− 5.25 to − 4.88) |
 K = 2 | − 2.27 (− 2.40 to − 2.13) | − 2.44 (− 2.58 to − 2.31) | − 2.41 (− 2.54 to − 2.27) | − 2.40 (− 2.55 to − 2.25) |
 K = 3 | − 0.15 (− 0.27 to − 0.03) | − 0.33 (− 0.46 to − 0.20) | − 0.29 (− 0.42 to − 0.17) | − 0.28 (− 0.42 to − 0.14) |
 Age (years) | − 0.02 (− 0.05 to − 0.00) | − 0.03 (− 0.05 to − 0.01) | − 0.03 (− 0.05 to 0.00) | − 0.06 (− 0.1 to − 0.02) |
 Partner age (years) | 0.01 (− 0.01 to 0.02) | 0.01 (0.00 to 0.02) | 0.01 (0.00 to 0.03) | 0.01 (− 0.00 to 0.03) |
 Sperm injected into egg | − 0.19 (− 0.35 to − 0.03) | − 0.33 (− 0.48 to − 0.18) | − 0.32 (− 0.48 to − 0.17) | − 0.31 (− 0.48 to − 0.15) |
 Number of oocytes | – | – | 0.22 (0.10 to 0.33) | − 0.18 (− 0.67 to 0.29) |
 Fertilisation rate | – | – | − 0.30 (− 0.41 to − 0.20) | − 0.60 (− 0.93 to − 0.13) |
Double embryo transfer submodel | ||||
 Intercept | 0.11 (0.06 to 0.17) | 0.13 (0.07 to 0.19) | 0.13 (0.06 to 0.19) | 0.08 (0.02 to 0.14) |
 Age (years) | 0.02 (0.01 to 0.04) | 0.02 (0.01 to 0.04) | 0.02 (0.00 to 0.03) | − 0.01 (− 0.03 to 0.01) |
 Partner age (years) | − 0.01 (− 0.02 to 0.00) | − 0.01 (− 0.02 to 0.00) | 0.00 (− 0.02 to 0.00) | − 0.00 (− 0.01 to 0.01) |
 Attempt no: 1st | 0 | 0 | 0 | 0 |
 2nd | 0.27 (0.15 to 0.39) | 0.23 (0.11 to 0.35) | 0.25 (0.13 to 0.37) | 0.27 (0.15 to 0.38) |
 3rd | 0.46 (0.23 to 0.70) | 0.44 (0.19 to 0.67) | 0.47 (0.23 to 0.72) | 0.53 (0.31 to 0.75) |
 4th or 5th | 0.72 (0.15 to 1.31) | 0.60 (0.06 to 1.17) | 0.63 (0.10 to 1.21) | 0.69 (0.16 to 1.25) |
 Number of oocytes | – | – | − 0.06 (− 0.13 to − 0.03) | − 0.25 (− 0.50 to 0.01) |
 Fertilisation rate | – | – | − 0.02 (− 0.09 to 0.05) | − 0.34 (− 0.51 to − 0.10) |
 Embryo evenness | – | – | − 0.14 (− 0.20 to − 0.08) | − 0.09 (− 0.15 to − 0.02) |
 Embryo fragmentation | – | – | − 0.12 (− 0.18 to − 0.06) | − 0.05 (− 0.12 to 0.03) |
Live birth event submodel | ||||
 Intercept | − 0.46 (− 0.51 to − 0.41) | − 0.49 (− 0.54 to − 0.44) | − 0.56 (− 0.64 to − 0.47) | − 0.39 (− 0.73 to − 0.04) |
 Age (years) | − 0.02 (− 0.04 to 0.00) | − 0.02 (− 0.04 to − 0.01) | − 0.01 (− 0.03 to 0.00) | − 0.03 (− 0.05 to − 0.01) |
 Partner age (years) | − 0.01 (− 0.02 to 0.00) | − 0.01 (− 0.02 to 0.00) | − 0.01 (− 0.02 to 0.00) | 0.00 (− 0.01 to 0.00) |
 Number of oocytes | – | – | 0.04 (− 0.03 to 0.12) | − 0.13 (− 0.31 to 0.08) |
 Fertilisation rate | – | – | 0.14 (0.07 to 0.21) | − 0.16 (− 0.39 to 0.12) |
 Embryo evenness | – | – | 0.07 (0.01 to 0.13) | 0.03 (− 0.04 to 0.10) |
 Embryo fragmentation | – | – | 0.04 (− 0.02 to 0.10) | 0.04 (− 0.04 to 0.11) |
 DET | – | – | 0.11 (0.01 to 0.22) | − 0.13 (− 0.66 to 0.43) |