Multivariate prediction of mixed, multilevel, sequential outcomes arising from in vitro fertilisation

Table 3 Performance metrics for the four sequential prediction models

	Pre-treatment separate	Pre-treatment joint	Dynamic separate	Dynamic joint
Number of oocytes (RMSE)	5.96	5.96	5.96	5.96
Fertilisation rate (RMSE)	2.88	2.83	2.80	2.86
Embryo evenness (RMSE)	1.00	1.00	1.02	1.02
Embryo fragmentation (RMSE)	1.09	1.08	1.08	1.12
DET (Brier score)	0.24	0.24	0.23	0.25
DET (AUC, 95% CI)	0.58, 0.55 to 0.60	0.58, 0.55 to 0.60	0.64, 0.62 to 0.66	0.58, 0.55 to 0.60
LBE (Brier score)	0.22	0.22	0.21	0.23
LBE (AUC, 95% CI)	0.55, 0.53 to 0.58	0.55, 0.53 to 0.58	0.60, 0.58 to 0.63	0.47, 0.44 to 0.49

RMSE Root mean squared error, AUC Area under receiver operating characteristic curve, CI Confidence interval

ISSN: 2397-7523