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Table 3 Prognostic factors for training improvement in verbal short-term memory

From: Prognostic factors for change in memory test performance after memory training in healthy older adults: a systematic review and outline of statistical challenges

Study

Test for outcome assessment

Dependent variable

Prognostic factor

Multiple regression

   

Age

Education

Sex

Neuropsychology

Imaging

Others

de Lange et al., [32]

Word list

Standardized residuals

    

White matter microstructure →

 

McDougall et al. [40]

HVLT

RBMT

Relative gains

↑

  

Pre-test score ↑

 

Ethnicity →

Neely and Bäckman [42]

Immediate recall of word list

Post-test scores

↓

↑

 

MMSE ↑

Pre-test score ↑ *

  

Rosi et al. [44]

Immediate recall of word list

Post-test scores

↓

  

Pre-test ↑*

Working memory ↓

Fluid ability ↓

Crystallized ability ↑*

Processing speed ↑

Short-term memory ↓

  

Sandberg et al. [45]

Number recall

Post-test scores

↓*

  

Episodic memory ↑*

Processing speed ↓

Working memory ↑*

Verbal knowledge ↑

  

Brooks et al. [8]

Name recall

Post-test scores

↑*

  

Pre-test score*

 

Pretraining x mnemonic training →

Correlation analysis

Mohs et al. [21]

HVLT

Post-test scores

→

→

→

  

Subjective reported memory →

Kirchhoff, Anderson, Smith, Barch et al., [22]

Recognition memory decisions

Change score

    

Activity in frontal cortex ↑

 

Kirchhoff, Anderson, Smith et al., [22]

Recognition memory decisions

Change score

    

Activity in hippocampus ↑

 

Andrewes et al. [26]

Face-name test

Change score

   

NART →

RAVT →

Warrington Forced Choice Recognition ↑

 

Depression →

Mattis dementia scale →

Bråthen et al. [29]

Immediate recall of word list

n.a.

    

Hippocampal volume ↑*

Amplitude of low frequency fluctuation ↓

Fractional amplitude of low frequency fluctuation ↓*

 

Finkel and Yesavage [35]

Immediate recall of word list

Gain scores

x

x

 

MMSE x

 

Openness of experience ↑*

Depression x

Extraversion x

Neuroticism x

Hill et al. [37]

Face-name recall

Standardized residual scores

     

Rated confidence ↑

Hill et al. [38]

Face-name recall

Performance changes

   

MMSE ↑

  

Group comparisons (ANOVA, t test)

Clark, Xu, Callahan et al., [30]

HVLT

RAVL

RBMT

Relative mean improvement

     

Obesity ↓*

Clark, Xu, Unverzagtet al., [31]

HVLT

RAVL

RBMT

Relative mean improvement

 

→

    

McDougall et al. [40]

HVLT

RBMT

n.a.

 

↓

   

Ethnicity (Blacks and Hispanics scored lower than Whites)

Mixed models

Tomaszewski Farias et al. [34]

HVLT

RAVL

RBMT

Normalized residuals

     

Activities of daily living ↑

López-Higes et al. [39]

Word list recall

Logical memory test

n.a.

     

Apolipoprotein E4 →

No clear reporting

Bissig and Lustig [28]

Rank-test

n.a.

↓

  

Crystallized intelligence ↑

  

de Lange et al., [33]

Word list

Standardized residuals

    

White matter microstructure ↑

 
  1. Studies are sorted according to the statistical method used for obtaining the prognostic factors
  2. HVLT Hopkins Verbal learning Task, MMSE Mini Mental State Examination, NART National Adult Reading Test, RAVL Rey Auditory Verbal Learning Test, RBMT Rivermead Behavioral Memory Test, ↑ the higher the prognostic factor, the higher the improvement/positive correlation, ↓ the lower the prognostic factor, the higher the improvement/negative correlation, → no direction of effect reported, * significant, x unclear reporting