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Table 1 Descriptive characteristics of the variables from the ovarian cancer and coronary artery disease datasets

From: Adaptive sample size determination for the development of clinical prediction models

Predictor

Statistics

Result

Missing values (%)

Ovarian cancer case study

 Age (years)

Mean (range)

48 (8-96)

0

 Maximum lesion diameter (mm)

Mean (range)

82 (8-760)

0

 Maximum diameter of solid part (mm)

Mean (range)

28 (0-380)

0

 Number of papillations (0-4)

Mean (range)

0.4 (0-4)

0

 Acoustic shadows (no/yes)

N yes (%)

743 (13%)

0

 Ascites (no/yes)

N yes (%)

720 (12%)

0

 Bilateral masses (no/yes)

N yes (%)

1141 (19%)

0

Coronary artery disease case study

 Age (years)

Mean (range)

64 (18-89)

0

 HDL cholesterol (mg/dL)

Mean (range)

56 (15-188)

312 (6.4%)

 LDL cholesterol (mg/dL)

Mean (range)

128 (21-341)

310 (6.3%)

 Logarithm of fibrinogen (log(mg/dL))

Mean (range)

5.9 (4.6-7.3)

119 (4.1%)

 Sex (male/female)

N male (%)

3028 (62%)

0

 Chest pain (no/yes)

N yes (%)

2987 (61%)

0

 Diabetes mellitus (no/yes)

N yes (%

757 (16%)

0

 Hypertension (no/yes)

N yes (%)

3730 (76%)

0

 Dyslipidaemia (no/yes)

N yes (%)

3115 (64%)

0

 c-Reactive protein > 1.00 mg/dL (no/yes)

N yes (%)

681 (14%)

96 (2%)

 Smoking status

  

640 (13%)

  Never

N (%)

2304 (54%)

 

  Former

N (%)

1088 (26%)

 

  Current

N (%)

856 (20%)