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Table 1 Descriptive characteristics of the variables from the ovarian cancer and coronary artery disease datasets

From: Adaptive sample size determination for the development of clinical prediction models

Predictor Statistics Result Missing values (%)
Ovarian cancer case study
 Age (years) Mean (range) 48 (8-96) 0
 Maximum lesion diameter (mm) Mean (range) 82 (8-760) 0
 Maximum diameter of solid part (mm) Mean (range) 28 (0-380) 0
 Number of papillations (0-4) Mean (range) 0.4 (0-4) 0
 Acoustic shadows (no/yes) N yes (%) 743 (13%) 0
 Ascites (no/yes) N yes (%) 720 (12%) 0
 Bilateral masses (no/yes) N yes (%) 1141 (19%) 0
Coronary artery disease case study
 Age (years) Mean (range) 64 (18-89) 0
 HDL cholesterol (mg/dL) Mean (range) 56 (15-188) 312 (6.4%)
 LDL cholesterol (mg/dL) Mean (range) 128 (21-341) 310 (6.3%)
 Logarithm of fibrinogen (log(mg/dL)) Mean (range) 5.9 (4.6-7.3) 119 (4.1%)
 Sex (male/female) N male (%) 3028 (62%) 0
 Chest pain (no/yes) N yes (%) 2987 (61%) 0
 Diabetes mellitus (no/yes) N yes (% 757 (16%) 0
 Hypertension (no/yes) N yes (%) 3730 (76%) 0
 Dyslipidaemia (no/yes) N yes (%) 3115 (64%) 0
 c-Reactive protein > 1.00 mg/dL (no/yes) N yes (%) 681 (14%) 96 (2%)
 Smoking status    640 (13%)
  Never N (%) 2304 (54%)  
  Former N (%) 1088 (26%)  
  Current N (%) 856 (20%)