Table 1 Descriptive characteristics of the variables from the ovarian cancer and coronary artery disease datasets
From: Adaptive sample size determination for the development of clinical prediction models
| Predictor | Statistics | Result | Missing values (%) |
|---|---|---|---|
| Ovarian cancer case study | |||
| Age (years) | Mean (range) | 48 (8-96) | 0 |
| Maximum lesion diameter (mm) | Mean (range) | 82 (8-760) | 0 |
| Maximum diameter of solid part (mm) | Mean (range) | 28 (0-380) | 0 |
| Number of papillations (0-4) | Mean (range) | 0.4 (0-4) | 0 |
| Acoustic shadows (no/yes) | N yes (%) | 743 (13%) | 0 |
| Ascites (no/yes) | N yes (%) | 720 (12%) | 0 |
| Bilateral masses (no/yes) | N yes (%) | 1141 (19%) | 0 |
| Coronary artery disease case study | |||
| Age (years) | Mean (range) | 64 (18-89) | 0 |
| HDL cholesterol (mg/dL) | Mean (range) | 56 (15-188) | 312 (6.4%) |
| LDL cholesterol (mg/dL) | Mean (range) | 128 (21-341) | 310 (6.3%) |
| Logarithm of fibrinogen (log(mg/dL)) | Mean (range) | 5.9 (4.6-7.3) | 119 (4.1%) |
| Sex (male/female) | N male (%) | 3028 (62%) | 0 |
| Chest pain (no/yes) | N yes (%) | 2987 (61%) | 0 |
| Diabetes mellitus (no/yes) | N yes (% | 757 (16%) | 0 |
| Hypertension (no/yes) | N yes (%) | 3730 (76%) | 0 |
| Dyslipidaemia (no/yes) | N yes (%) | 3115 (64%) | 0 |
| c-Reactive protein > 1.00 mg/dL (no/yes) | N yes (%) | 681 (14%) | 96 (2%) |
| Smoking status | 640 (13%) | ||
| Never | N (%) | 2304 (54%) | |
| Former | N (%) | 1088 (26%) | |
| Current | N (%) | 856 (20%) | |