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Table 1 Potential prognostic factors considered for inclusion within the prognostic model

From: The development and validation of prognostic models for overall survival in the presence of missing data in the training dataset: a strategy with a detailed example

Potential prognostic factor

Description

Type

Age

Age derived at trial registration

Continuous

WHO PS

World Health Organisation Performance Status, a measure of the patient’s ability to do daily tasks

Ordinal range from 0 (alive and fully active) to 5 (dead)

LDH

Lactate dehydrogenase level in the blood, a measure of tissue damage

Continuous

CRP

C-reactive protein level in the blood, a measure of inflammation

Continuous

L:W

Lymphocyte count to total white blood cell count ratio

Continuous

ISS

International Staging System, a measure of the severity of disease in multiple myeloma calculated dependent on the levels of β2-microglobulm and albumin in the blood

Ordinal range from stage I to stage III