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Fig. 4 | Diagnostic and Prognostic Research

Fig. 4

From: Development, validation and clinical usefulness of a prognostic model for relapse in relapsing-remitting multiple sclerosis

Fig. 4

Decision curve analysis showing the net benefit of the prognostic model per cycle. The horizontal axis is the threshold estimated probability of relapsing within 2 years, a%, and the vertical axis is the net benefit. The plot compares the clinical benefit of three approaches: “as per standard care for all” approach, “more active care for all” approach, and “decision based on the prognostic model” approach (see definitions in “Clinical benefit of the developed model”). For a given threshold probability, the approach with the highest net benefit is considered the most clinically useful model. The decision based on the prognostic model approach provides the highest net benefit for threshold probabilities ranging from 15 to 30%

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