Table 1 Bayesian latent class analysis-derived diagnostic accuracies of tests for each form of extrapulmonary TB
Culture | Xpert | Smear microscopy | Cytopathology/Histopathology | ADA | |
|---|---|---|---|---|---|
TB lymphadenitis | |||||
Sensitivity (%) (95% CrI) | 90.1 (80.3, 95.4) | 86.6 (77.2, 92.2) | 26.8 (20.6, 33.7) | 98.7 (96.1, 99.7) | NA |
Specificity (%) (95% CrI) | 99.3 (96.2,100) | 98.5 (94.4, 100) | 99.4 (97.0, 100) | 83.5 (74.6, 93.2) | NA |
TB meningitis | |||||
Sensitivity (%) (95% CrI) | 60.5 (43.2, 82.7) | 52.6 (36.2, 73.3) | 27.5 (14.9, 42.6) | NA | 83.1 (64.8, 94.5) |
Specificity (%) (95% CrI) | 99.2 (96.8, 100) | 99.5 (97.6, 100) | 98.6 (96.3, 99.7) | NA | 90.7 (83.8, 98.1) |
TB pleuritis | |||||
Sensitivity (%) (95% CrI) | 75.4 (56.1, 94.5) | 37.7 (27.2, 49.8) | 15.4 (9.4, 23.4) | NA | 94.6 (88.8, 98.1) |
Specificity (%) (95% CrI) | 99.4 (97.3, 100) | 96.9 (93.8, 99.0) | 99.3 (97.7, 99.9) | NA | 74.7 (65.1, 90.3) |