Table 1 Study participants characteristics, stratified by data cohort
| Â | Derivation cohort | Geographic validation cohort | SMD | Missing values (%) |
|---|---|---|---|---|
n | 1588 | 1211 | Â | Â |
Female sex (%) | 765 (48.2) | 520 (42.9) | 0.105 | 0.0 |
Age at presentation in years (median [IQR]) | 44.00 [30.00, 56.00] | 38.00 [29.00, 56.00] | 0.122 | 0.0 |
Body mass index in kg/m2 (median [IQR]) | 24.65 [22.27, 28.05] | 24.22 [21.77, 27.34] | 0.098 | 0.3 |
Number of comorbidities (median [IQR]) | 0.00 [0.00, 1.00] | 0.00 [0.00, 1.00] | 0.020 | 0.0 |
Presence of at least one cardiovascular risk factor (%) | 489 (30.9) | 361 (29.9) | 0.023 | 0.4 |
Number of acute COVID-19 symptoms (median [IQR]) | 5.00 [3.00, 6.00] | 5.00 [3.00, 6.00] | 0.041 | 0.0 |
Severity of acute COVID-19 (%) | Â | Â | 0.316 | 0.0 |
   Outpatients | 1395 (87.8) | 941 (77.7) |  |  |
   Ward | 147 (9.3) | 151 (12.5) |  |  |
   ICU/IMC | 46 (2.9) | 119 (9.8) |  |  |
Responsibility for childcare/family member (median [IQR]) | 1.00 [1.00, 4.00] | 1.00 [1.00, 3.00] | 0.160 | 1.6 |
Main responsibility for household (%) | Â | Â | 0.026 | 0.9 |
   No | 368 (23.4) | 294 (24.5) |  |  |
   Partners contributed  approximately equally | 533 (33.9) | 398 (33.1) |  |  |
   Yes or live alone | 672 (42.7) | 509 (42.4) |  |  |
Feeling of stress at home (1 no, 10 max) (median [IQR]) | 3.00 [2.00, 5.00] | 3.00 [2.00, 5.00] | 0.084 | 0.7 |
Study site | Â | Â | Â | 0.0 |
   University Hospital Basel | 1588 (100.0) | 0 (0.0) |  |  |
   University Hospital Zurich | 0 (0.0) | 897 (74.1) |  |  |
   University Hospital Bern | 0 (0.0) | 36 (3.0) |  |  |
   Cantonal Hospital Baden | 0 (0.0) | 278 (23.0) |  |  |