Fig. 5From: A novel method for interrogating receiver operating characteristic curves for assessing prognostic testsMultivariable modelling. Two possible prognostic test permutations for pre-eclampsia prediction in first-time pregnant women are shown (hypothetical data) (a). Rule-in test compliant with pre-set test specification: PPV ≥ 0.133, S n ≥ 0.50, for a 5% disease prevalence. b Rule-out test compliant with pre-set test specification: NPV ≥ 0.988, S p ≥ 0.50, for a 5% disease prevalenceBack to article page