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Table 2 Predictors of death/MI/stroke in univariate Cox model

From: Development of a risk score to identify patients with type 2 diabetes mellitus and multivessel coronary artery disease who can defer bypass surgery

Variable

HR

95% CI

P value

Age (per 1 year increase)

1.041

(1.017, 1.066)

<.001

Gender, female (vs. male)

0.767

(0.481, 1.225)

0.27

Race, White (vs. non-White)

0.901

(0.587, 1.385)

0.22

Glycemic arm treatment, insulin providing (vs. insulin sensitizing)

0.885

(0.613, 1.276)

0.51

History of insulin use

1.472

(0.984, 2.200)

0.06

History of MI

0.708

(0.476, 1.054)

0.09

History of CHF

2.699

(1.361, 5.350)

0.005

Hypertension

1.433

(0.818, 2.508)

0.21

Hypercholesterolemia

0.655

(0.431, 0.995)

0.047

Cerebrovascular accident, TIA

1.591

(0.892, 2.840)

0.12

Prior revascularization

1.482

(0.929, 2.362)

0.10

Current smoker

0.997

(0.548, 1.815)

0.99

Angina equivalent

1.055

(0.724, 1.537)

0.78

Angina class (vs. no angina)

 Stable 1, 2

0.831

(0.560, 1.232)

0.85

 Stable 3, 4

1.291

(0.632, 2.637)

0.49

 Unstable

1.230

(0.526, 2.879)

0.23

Weight (kg) (per 1 year increase)

1.000

(0.990, 1.011)

0.94

BMI (per 1 unit increase)

0.993

(0.957, 1.031)

0.73

Systolic blood pressure (per 1 unit increase)

1.008

(1.000, 1.017)

0.05

Diastolic blood pressure (per 1 unit increase)

0.996

(0.978, 1.015)

0.69

Ankle brachial index (per 1 unit increase)

0.899

(0.416, 1.943)

0.79

Serum creatinine (mg/dl) (per 1 unit increase)

2.679

(1.399, 5.128)

0.003

Urine albumin/creatinine ratio mg/g, (per 100 unit increase)

1.041

(1.020, 1.063)

<.001

Circulating insulin (IU/ml) (per 1 unit increase)

1.015

(1.002, 1.029)

0.023

HbA1c (%) (per 1 unit increase)

1.057

(0.949, 1.178)

0.32

HDL cholesterol (mg/dl) (per 1 unit increase)

0.986

(0.967, 1.006)

0.16

LDL cholesterol (mg/dl) (per 1 unit increase)

0.998

(0.992, 1.004)

0.50

Triglycerides (mg/dl) (per 1 unit increase)

0.976

(0.837, 1.139)

0.76

Myocardial jeopardy (per 1 unit increase)

1.012

(1.003, 1.021)

0.007

Non-sublingual nitrate

1.130

(0.767, 1.666)

0.54

Anti-platelet

1.168

(0.705, 1.935)

0.55

Aspirin

1.057

(0.593, 1.885)

0.85

Statin

1.108

(0.710, 1.729)

0.65

ACE/ARB

1.160

(0.722, 1.864)

0.54

Beta-blocker

0.837

(0.554, 1.265)

0.40

Aspirin, statin, ACE/ARB, beta-blocker

1.248

(0.865, 1.801)

0.24

  1. MI myocardial infarction, CHF congestive heart failure, TIA transient ischemic attack, BMI body mass index, HbA1c hemoglobin A1c, HDL high-density lipoprotein, LDL low-density lipoprotein, ACE angiotensin-converting enzyme inhibitor, ARB aldosterone receptor blocker. Cox model comparison is against absence of the variable if no comparison is listed
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Diagnostic and Prognostic Research

ISSN: 2397-7523

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