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Table 1 Relevant issues in deriving evidence-supported state of the art guidance for multivariable modelling

From: State of the art in selection of variables and functional forms in multivariable analysis—outstanding issues

No.

Item

1

Investigation and comparison of the properties of variable selection strategies

2

Comparison of spline procedures in both univariable and multivariable contexts

3

How to model one or more variables with a ‘spike-at-zero’?

4

Comparison of multivariable procedures for model and function selection

5

Role of shrinkage to correct for bias introduced by data-dependent modelling

6

Evaluation of new approaches for post-selection inference

7

Adaption of procedures for very large sample sizes needed?