From: Risk of bias of prognostic models developed using machine learning: a systematic review in oncology
 | All (n = 62) | Development only (n = 48) | Development and external validation (n = 14) |
---|---|---|---|
 | n (%) | n (%) | n (%) |
Development characteristics | |||
Data source* | |||
  Randomised controlled trial | 1 (1.6) | - | 1 (7.1) |
  Prospective cohort | 9 (14.5) | 9 (18.8) | - |
  Retrospective cohort | 14 (22.6) | 11 (22.9) | 3 (21.4) |
  Registry | 21 (33.9) | 15 (31.3) | 6 (42.9) |
  Routine care database | 9 (14.5) | 7 (14.6) | 2 (14.3) |
  Other** | 3 (4.8) | 2 (4.2) | 1 (7.1) |
  Unclear | 5 (8.1) | 4 (8.3) | 1 (7.1) |
Setting*** | |||
  Primary care | 2 (3.2) | 2 (4.2) | - |
  Secondary care | 36 (58.1) | 29 (60.4) | 7 (50) |
  Tertiary care | 10 (16.1) | 7 (14.6) | 3 (21.4) |
  General population | 5 (8.1) | 3 (6.3) | 2 (14.3) |
  Other**** | 3 (4.8) | 3 (6.3) | - |
  Unclear | 6 (9.7) | 4 (8.3) | 2 (14.3) |
Multicentre***** | |||
  No | 26 (41.9) | 24 (50) | 2 (14.3) |
  Yes | 13 (21) | 7 (14.6) | 6 (42.9) |
  Unclear | 23 (37.1) | 17 (35.4) | 6 (42.9) |
Geographic location****** | |||
  South America | 2 (3.2) | 2 (4.2) | - |
  Asia | 8 (12.9) | 6 (12.5) | 2 (14.3) |
  Europe | 13 (21) | 13 (27.1) | - |
  Canada | 3 (4.8) | 3 (6.3) | - |
  USA | 21 (33.9) | 15 (31.3) | 6 (42.9) |
  Europe, North America, Australia | 1 (1.6) | 1 (2.1) | - |
  Europe, South America | 1 (1.6) | - | 1 (7.1) |
  South Asia, USA | 1 (1.6) | 1 (2.1) | - |
  Unclear | 12 (19.4) | 7 (14.6) | 5 (35.7) |
Intended user | |||
  Health care providers | 34 (54.8) | 27 (56.3) | 7 (50) |
  Public/patients | 2 (3.2) | 2 (4.2) | - |
  Researchers | 1 (1.6) | 1 (2.1) | - |
  Health care providers and patient/public | 4 (6.5) | 1 (2.1) | 3 (21.4) |
  Health care providers and researchers | 2 (3.2) | 2 (4.2) | - |
  Unclear | 19 (30.6) | 15 (31.3) | 4 (28.6) |
  Aim of model |  |  |  |
  Predict risk | 36 (58.1) | 25 (52.1) | 11 (78.6) |
  Classify patients | 25 (40.3) | 23 (47.9) | 2 (14.3) |
  Predict length of stay (continuous outcome) | 1 (1.6) | - | 1 (7.1) |